Elevated triglyceride-glucose index and its combination with anthropometric indices as indicators of the risk of new-onset transient ischemic attack: a prospective cohort study
Background The association between the triglyceride-glucose (TyG) and combined anthropometric indices with transient ischemic attack (TIA) has not previously been explored in detail. This study investigated the relationship of TyG and anthropometric indices with incident TIA in healthy populations. Methods Data from a prospective UK Biobank cohort (361,336 participants) were analyzed using Cox regression, population attributable fraction (PAF), restricted cubic splines (RCS), and receiver operating characteristic (ROC) curves. Robustness was evaluated using subgroup and interaction analyses and sensitivity tests. Results During a median follow-up of 13.7 years, TyG, glucose triglyceride-waist circumference (TyG-WC), glucose triglyceride-body mass index (TyG-BMI), glucose triglyceride-waist height ratio (TyG-WHtR), visceral adiposity index (VAI), and lipid accumulation product (LAP) were significantly associated with increased TIA risk (all P
Background The association between the triglyceride-glucose (TyG) and combined anthropometric indices with transient ischemic attack (TIA) has not previously been explored in detail. This study investigated the relationship of TyG and anthropometric indices with incident TIA in healthy populations. Methods Data from a prospective UK Biobank cohort (361,336 participants) were analyzed using Cox regression, population attributable fraction (PAF), restricted cubic splines (RCS), and receiver operating characteristic (ROC) curves. Robustness was evaluated using subgroup and interaction analyses and sensitivity tests. Results During a median follow-up of 13.7 years, TyG, glucose triglyceride-waist circumference (TyG-WC), glucose triglyceride-body mass index (TyG-BMI), glucose triglyceride-waist height ratio (TyG-WHtR), visceral adiposity index (VAI), and lipid accumulation product (LAP) were significantly associated with increased TIA risk (all P
What's Your Reaction?
:max_bytes(150000):strip_icc()/GettyImages-2187410260-5afe56694791404f99c253dd8d5abe6a.jpg?#)
